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human breast cancer cell line hcc1599  (ATCC)


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    Structured Review

    ATCC human breast cancer cell line hcc1599
    Human Breast Cancer Cell Line Hcc1599, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 80 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+breast+cancer+cell+line+hcc1599/HCC1599/pm42097228-243-27-33
    Average 94 stars, based on 80 article reviews
    human breast cancer cell line hcc1599 - by Bioz Stars, 2026-10
    94/100 stars

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    Article Title: In vivo genetic circuit drives systemic PARP1 siRNA assembly into small extracellular vesicles for BRCA2-deficient breast cancer therapy.
    Article Snippet: Rationale: BRCA2-mutant breast cancer is a major clinical challenge, with current poly ADPribose polymerase inhibitor (PARPi) therapies limited by systemic toxicity and acquired resistance.. This study aimed to develop a RNA interference (RNAi) strategy to selectively inhibit PARP1 in breast tumors via a systemic, non-viral delivery platform.. Methods: We designed a genetic circuit as a naked DNA plasmid, encoding a PARP1-specific siRNA embedded within a pre-miR-155 backbone under the control of a cytomegalovirus (CMV) promoter.



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    94
    ATCC human breast cancer cell line hcc1599
    Human Breast Cancer Cell Line Hcc1599, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+breast+cancer+cell+line+hcc1599/HCC1599/pm42097228-243-27-33
    Average 94 stars, based on 1 article reviews
    human breast cancer cell line hcc1599 - by Bioz Stars, 2026-10
    94/100 stars
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